> R&D > Protein Technology > Cytoplasmic Transduction Peptide (CTP) TechnologyDrug delivery system
CTP technology can effectively deliver polymeric molecules to cytoplasm. Therefore, it is highly useful as a drug delivery system (DDS) when the drug has to perform its biological activation role through its action on the cytoplasm.
Drug bound to the CTP can display effective results even at low concentration due to the improved efficacy in cell membrane penetration. In particular, in the event the drug to be used induces genetic abnormality, CTP technology that blocks nuclear import can be applied usefully.
Dendritic cell antigen delivery technology
Our antigen delivery technology is able to induce high level of sensitization effects and immune reactions on a diverse range of targets. The reason is because the recombinant proteins manufactured by fusing our patented CTP with the selected antigens induce cancer-specific immunity in dendritic cell treatment.
Technology transfer and joint research and development
JW CreaGene always welcomes consultations and inquiries on the CTP related technology transfer and joint research and development.
CTP512 has cell penetrating capability that is more than time higher than PTD. which is the best known existing cell penetrating peptide.
Protein combined with CTP512 stays in the cytoplasm while the majority of PTD moves to the nucleus.
* CTP512: CTP sequence with the most outstanding cell penetration