In general, antigens refer to all the substances deemed to be foreign matters in a living organism. Although majority of the antigens are pathogens or viral proteins, a wide range of substances including polysaccharides, artificially synthesized substances and mutant cells that are generated in the body (cancer cell), etc. can also act as antigens. Antigens are divided into 3 types. The first, immunogen, is the substance that induces immune reaction when it enters the body with the extent of the immune reaction determined by its concentration, its molecular size and the differences in the chemical composition. The second, tolerogen, is The substance that induces immunological tolerance due to the molecular structure and can be converted into immunogen if the molecular structure changes. The third, allergen, is the substance that induces allergic reaction and enters the body through routes including digestive system, absorption, injection and skin contact, etc. These antigens are used in dendritic cells manufacturing and dendritic cells introduced to the patient’s body manifests treatment effects by inducing anti-cancer and anti-inflammation reactions by the T cells.
JW CreaGene holds many antigens that induce powerful immunogenicity against cancer along with antigens that induce immunological tolerance. Recently, we have been spurring on with the improvement of the functions of the dendritic cell therapeutics through the discovery and development of universal antigens and stem cell cancer antigens.
Product name | Abbreviations | Serial position | Molecular weight | Purity /concentration |
300㎍ | 500㎍ |
---|---|---|---|---|---|---|
Human Prostate Data sheetSpecific Antigen |
hPSA | 33-386 | 29.7kDa | More than 95% / 0.3~0.4mg/ml |
300,000 | 500,000 |
Human Prostatic Data sheetAcid Phosphatase |
hPAP | 18-261 | 43.8kDa | |||
Human Vimentin Data sheet |
hVIM | 1-466 | 54.8kDa | |||
Human Data sheetAlpha-Enolase |
hENO | 1-434 | 48.1kDa | |||
Human Survivin Data sheet |
hSVV | 1-142 | 16.2kDa |